Thursday, September 22, 2011

Playing Games to Fight HIV

Gamers were able to find come up with the answer faster than then computers. There is some real potential here.

"A couple of years ago, I told you about Foldit, a computer game that harnesses the power of human putzing to help scientists unravel the mysteries of protein structure. There's a new research paper out that uses results from Foldit as a basis for a new proposed structure of a key protein in a virus that is a relative of HIV.

As important as proteins are, we know relatively little about how and why these complex chains of amino acids fold and twist the way they do and how that structure relates to function. Foldit takes advantage of the fact that, given the right rules, people can come up with possible, plausible protein structures far faster than a computer program can factor out all the possible permutations. And that's why Foldit players—citizen scientists of a sort—were so useful in this case.

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